E. Shlush

Inflammatory signals from fatty bone marrow supports the early stages of DNMT3a driven clonal hematopoiesis

This study shows that fatty bone marrow (FBM) promotes DNMT3A-driven clonal hematopoiesis by enhancing inflammatory signals like IL-6, which can be inhibited by blocking the IL-6 receptor.

TTYH family members form tetrameric complexes within the cell membrane

This study shows that mTTYH1 and mTTYH3 form tetramers at the plasma membrane, which dissociate into dimers upon detergent solubilization.