Dexamethasone Enhances CAR T Cell Persistence and Function by Upregulating Interleukin 7 Receptor
A. Munoz, R. Urak, E. Taus, H.-J. Hsieh, K. Jin, S.-H. Lin, D. Awuah, V. Vyas, S. J. Priceman, M. Clark, S. Forman, X. Wang
This study shows dexamethasone enhances CAR T cell persistence and function by upregulating IL7R, improving anti-tumor efficacy in vivo.
bioRxiv · Aug 29, 2022 · PreprintImmunology