Latent Plasticity of Effector-like Exhausted CD8 T cells contributes to memory responses
S. Raju, Y. Xia, B. Daniel, K. E. Yost, E. Bradshaw, E. Tonc, D. J. Verbaro, A. T. Satpathy, T. Egawa
The paper identifies a subset of exhausted CD8 T cells with plasticity to reprogram into memory cells, suggesting new targets for immunotherapy.
bioRxiv · Feb 22, 2020 · PreprintImmunology