A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets
D. Calebiro, S. L. O'Brien, E. Tripp, G. Smith, A. Boufersaoui, J. Roberts, J. A. Pike, J. Correia, T. A. Miljus, D. A. Tennant, B. D. Hudson, G. Milligan, Z. Gerhart-Hines, T. W. Schwartz
The paper shows FFA4, a GPCR, signals from lipid droplet-associated membranes in adipocytes, providing localized feedback to regulate lipolysis.
bioRxiv · Jul 28, 2023 · PreprintPharmacology & Toxicology