Author

J. A. Pike

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Boufersaoui· 1 shared A. Maclachlan· 1 shared A. O. Khan· 1 shared A. Slater· 1 shared B. D. Hudson· 1 shared C. O'Shea· 1 shared C. Pallini· 1 shared D. A. Tennant· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Boufersaoui

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Author profile →

4 papers

Recent·Most cited

A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets

D. Calebiro, S. L. O'Brien, E. Tripp, G. Smith, A. Boufersaoui, J. Roberts, J. A. Pike, J. Correia, T. A. Miljus, D. A. Tennant, B. D. Hudson, G. Milligan, Z. Gerhart-Hines, T. W. Schwartz

The paper shows FFA4, a GPCR, signals from lipid droplet-associated membranes in adipocytes, providing localized feedback to regulate lipolysis.

bioRxiv · Jul 28, 2023 · PreprintPharmacology & Toxicology

A framework for evaluating the performance of SMLM cluster analysis algorithms

D. J. Nieves, J. A. Pike, F. Levet, J. Griffie, D. Sage, E. A. K. Cohen, J.-B. Sibarita, M. Heilemann, D. M. Owen

The paper evaluates SMLM cluster analysis algorithms using ARI and IoU metrics across simulated scenarios to establish a standard framework for future algorithm development.

bioRxiv · Jun 19, 2021Biophysics

Post-translational polymodification of β1 tubulin regulates motor protein localisation in platelet production and function

A. O. Khan, A. Slater, A. Maclachlan, P. L. Nicolson, J. A. Pike, J. S. S. Reyat, J. Yule, R. Stapley, S. G. Thomas, N. V. Morgan

The paper investigates how post-translational polymodifications of β1 tubulin regulate motor protein localization in platelet production and function using patient data, iPSC-derived megakaryocytes, and platelets.

Haematologica · Dec 17, 2020Peer-reviewedCell Biology

Immobilised collagen prevents shedding and induces sustained GPVI clustering and signalling in platelets.

C. Pallini, J. A. Pike, C. O'Shea, R. K. Andrews, E. E. Gardiner, S. P. Watson, N. S. Poulter

This study shows immobilized collagen prevents GPVI shedding and sustains its clustering and signaling in platelets for at least 3 hours.

bioRxiv · Jul 7, 2020 · PreprintCell Biology