Tertiary structure and conformational dynamics of the anti-amyloidogenic chaperone DNAJB6b at atomistic resolution
V. Adupa, E. Ustyantseva, H. H. Kampinga, P. R. Onck
This study reveals the tertiary structure and conformational dynamics of DNAJB6b at atomistic resolution, showing it cycles between three states and has an autoinhibitory mechanism linked to disease mutations.
bioRxiv · Jun 15, 2023Biophysics