Author

E. Yaffe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. A. Relman· 2 shared L. Dethlefsen· 2 shared A. Aranda-Diaz· 1 shared A. D. Patterson· 1 shared A. V. Patankar· 1 shared C. Gui· 1 shared D. Relman· 1 shared D. Shalon· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersEvolutionary Biology

D. A. Relman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A short course of antibiotics selects for persistent resistance in the human gut

E. Yaffe, L. Dethlefsen, A. V. Patankar, C. Gui, S. Holmes, D. A. Relman

This study shows that short antibiotic use in humans leads to persistent resistance in gut bacteria through convergent evolution and selective sweeps.

bioRxiv · Sep 4, 2023 · PreprintEvolutionary Biology

Profiling of the human intestinal microbiome and bile acids under physiologic conditions using an ingestible sampling device

D. Shalon, R. N. Culver, J. A. Grembi, J. Folz, P. Treit, L. Dethlefsen, X. Meng, E. Yaffe, S. Spencer, H. Shi, A. Aranda-Diaz, A. D. Patterson, G. Triadafilopoulos, S. P. Holmes, M. Mann, , K. Huang

The paper develops an ingestible device to collect intestinal samples and identifies regional differences in microbiota and bile acids compared to stool.

bioRxiv · Jan 19, 2022 · PreprintMicrobiology

Tracking microbial evolution in the human gut using Hi-C

D. A. Relman, E. Yaffe

The paper uses Hi-C and probabilistic modeling to track microbial evolution in the human gut, revealing accessory element exchange and core genome adaptation over time.

bioRxiv · Mar 31, 2019Microbiology