GenomicsbioRxivPreprint
Unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution
Monique A.J. van Eijndhoven, Ernesto Aparicio‐Puerta, Cristina Gómez‐Martín…·Dirk Michiel Pegtel
The paper introduces IsoSeek, a method for unbiased and UMI-informed sequencing of cell-free miRNAs, revealing extensive uridylation of disease-associated miRNAs and improving isomiR detection in extracellular vesicles.
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