NeurosciencebioRxivPreprint
The inflammatory micro-environment induced by targeted CNS radiotherapy is underpinned by disruption of DNA methylation
Thomas O Millner, Pratistha Panday, Yu Xiao…·Silvia Marino
This study shows that targeted CNS radiotherapy disrupts DNA methylation and induces neuroinflammation through epigenetic changes in brain tissue and cerebral organoids.
DOI 10.1101/2024.03.04.581366