Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds
Izabela Kowalczyk, Chanjae Lee, Elisabeth Schuster, Josefine Hoeren, Valentina Trivigno, Levin Riedel, Jessica Görne, John B. Wallingford, Annette Hammes, Kerstin Feistel
The paper investigates the role of Lrp2 in neural tube closure using mouse and Xenopus models, identifying its interaction with Shroom3 and Gipc1 and its role in apical constriction and planar cell polarity.
Development · Jan 15, 2021Peer-reviewedDevelopmental Biology