MicrobiologybioRxivPreprint
The innate immune protein calprotectin incapacitates the bactericidal activity of β-lactam antibiotics
Amanda Z. Velez, Jana N. Radin, Emily N. Kennedy…·Brian P. Conlon
This study shows that calprotectin reduces β-lactam antibiotic efficacy by inactivating bacterial autolysins through zinc sequestration, independent of bacterial growth.
2 citations