Emma Smith

Insulin controls olfactory gain at the first central synapse by regulating periglomerular neuron excitability

The paper shows insulin reduces olfactory sensitivity by inhibiting periglomerular neurons in mice, altering sensory input before it reaches mitral cells.

Distinct distributions of myosin motor conformations during contraction of slow and fast skeletal muscle

The paper uses X-ray diffraction to show that fewer myosin motors are attached to actin in slow compared to fast skeletal muscle, revealing distinct structural and signaling mechanisms.

Broadly Reactive Anti-VHH Antibodies for Characterizing, Blocking, or Activating Nanobody-Based CAR-T Cells

The paper develops anti-VHH antibodies that target nanobody domains in CAR-T cells, enabling labeling, blocking, and activation of VHH-based CAR-T cells without disrupting antigen binding.

Multi-omics identification of extracellular components of the fetal monkey and human neocortex.

The paper identifies extracellular components in the developing fetal neocortex of humans and non-human primates using multi-omics approaches.

Comparative phenotypic, genomic and transcriptomic characterisation of two Salmonella Typhimurium strains for a first-in-human challenge model

The paper characterizes two Salmonella Typhimurium strains for a first-in-human challenge model, confirming their genomic and phenotypic stability post-manufacture.