BioinformaticsbioRxivPreprint
Delineating genotypes and phenotypes of individual cells from long-read single cell transcriptomes
Cheng-Kai Shiau, Lina Lu, Rachel E. Kieser…·Ruli Gao
The paper introduces scNanoGPS, a toolkit for analyzing long-read single-cell transcriptomes to infer cell genotypes and phenotypes without short-read data, revealing cell-type-specific isoform and mutation patterns in tumors.