GeneticsbioRxiv
Systematic over-expression screens for chromosome instability identify conserved dosage chromosome instability genes in yeast and human tumors
Supipi Duffy, Hok Khim Fam, Yikan Wang…·Phillip Hieter
The paper identifies conserved genes involved in chromosome instability through over-expression screens in yeast and human cells, highlighting Tdp1 and Taf12 as potential therapeutic targets.