Rescue of SARS-CoV-2 from a single bacterial artificial chromosome
C. Ye, J.-G. Park, F. Oladunni, R. N. Platt, T. Anderson, F. Almazan, J. C. de la Torre, L. Martinez-Sobrido
The paper develops an infectious SARS-CoV-2 cDNA clone using a bacterial artificial chromosome, which replicates similarly to the natural virus in cell cultures and animal models.
bioRxiv · Jul 22, 2020Microbiology