Cancer BiologybioRxiv
A PTP1B-Cdk3 signaling axis promotes cell cycle progression of human glioblastoma cells through an Rb-E2F dependent pathway
O. Villamar-Cruz, M. A. Loza-Mejia, A. Vivar-Sierra…·L. E. Arias-Romero
This study identifies a PTP1B-Cdk3 signaling axis that promotes glioblastoma cell cycle progression via Rb-E2F pathway, showing PTP1B dephosphorylates Cdk3 and inhibits its activity.
DOI 10.1080/10985549.2023.2273193