The extracellular matrix supports breast cancer cell growth under amino acid starvation by promoting tyrosine catabolism
M. Nazemi, B. Yanes, M. Llanses Martinez, H. Walker, F. Bard, E. Rainero
This study shows that the extracellular matrix supports breast cancer cell growth under amino acid starvation by enhancing tyrosine catabolism through ECM uptake and lysosomal degradation.
bioRxiv · Jun 9, 2021 · PreprintCancer Biology