Author

S.-C. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:human· 5 Assay:proteomics· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2

Frequent Co-Authors

J. Xiao· 2 shared A. Prakash· 1 shared A. Wu· 1 shared A.-P. Chen· 1 shared B. Henson· 1 shared B.-Y. Li· 1 shared C. H. Kuo· 1 shared C. Liang· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBiophysics

J. Xiao

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Author profile →

9 papers

Recent·Most cited

A packaging signal-binding protein regulates the assembly checkpoint of integrative filamentous phages

T.-Y. Yeh, M. C. Feehley, P. J. Feehley, V. Y. Ooi, Y.-Y. Hung, S.-C. Wang, G. P. Contreras

The paper identifies PSB15 as a protein essential for integrative filamentous phage assembly, showing it binds packaging signals and interacts with host proteins to regulate the assembly checkpoint.

bioRxiv · Mar 19, 2024 · PreprintMicrobiology

The natural tannins oligomeric proanthocyanidins and punicalagin are potent inhibitors of infection by SARS-CoV-2 in vitro

H.-F. Chen, W.-J. Wang, C.-Y. Chen, W.-C. Chang, P.-R. Hsueh, S.-L. Peng, C.-S. Wu, Y. Chen, H.-Y. Huang, W.-J. Shen, S.-C. Wang, M.-C. Hung

This study identifies OPCs and punicalagin as potent inhibitors of SARS-CoV-2 infection, with punicalagin showing the strongest activity against omicron variants and viral entry.

bioRxiv · Jan 12, 2023Microbiology

Development of a soil inoculation method coupled with blocker-mediated 16S rRNA gene amplicon sequencing reveals the effect of antibacterial T6SS on agrobacteria tumorigenesis and gallobiome composition

S.-C. Wang, A.-P. Chen, S.-J. Chou, C. H. Kuo, E.-M. Lai

This study develops a soil inoculation method with blocker-mediated 16S rRNA gene sequencing to show that the T6SS in Agrobacteria promotes tumorigenesis and affects gallobiome composition through interbacterial competition.

bioRxiv · Oct 28, 2022Microbiology

PDR6-mediated camalexin efflux and disease resistance are regulated through direct phosphorylation by the kinases OXI1 and AGC2-2

G. Miao, J. Han, C.-x. Liu, J. Liu, C.-r. Wang, S.-c. Wang

This study identifies OXI1 and AGC2-2 as kinases that phosphorylate PDR6, enhancing camalexin efflux and disease resistance in plants.

bioRxiv · Feb 8, 2022 · PreprintPlant Biology

Protein detection in blood with single-molecule imaging

C.-P. Mao, S.-C. Wang, Y.-P. Su, S.-H. Tseng, L. He, A. Wu, R. Roden, J. Xiao, C.-F. Hung

This paper introduces SMAC, a single-molecule imaging technique that detects disease-specific proteins in blood samples at subfemtomolar concentrations.

bioRxiv · May 19, 2021Biophysics

Src activates retrograde membrane traffic through phosphorylation of GBF1

J. Chia, S.-C. Wang, S. Wee, D. J. Gill, F. Tay, S. Kannan, C. S. Verma, J. Gunaratne, F. Bard

This study identifies how Src kinase promotes retrograde membrane traffic by phosphorylating GBF1, facilitating its interaction with Arf1 and enabling GALNTs relocation from Golgi to ER.

bioRxiv · Aug 2, 2020Cell Biology

Accurate Diagnosis of Colorectal Cancer Based on Histopathology Images Using Artificial Intelligence

K.-S. Wang, G. Yu, C. Xu, X.-H. Meng, J. Zhou, C. Zheng, Z. Deng, L. Shang, R. Liu, S. Su, X. Zhou, Q. Li, J. Li, J. Wang, K. Ma, , H.-W. Deng

This paper develops an AI tool for colorectal cancer diagnosis using histopathology images, achieving high accuracy and consistency across multiple centers.

bioRxiv · Mar 15, 2020Pathology

Development and Application of a High-Content Virion Display Human GPCR Array

G.-D. Syu, S.-C. Wang, G. Ma, S. Liu, D. Pearce, A. Prakash, B. Henson, L.-C. Weng, D. Ghosh, P. Ramos, D. Eichinger, I. Pino, X. Dong, J. Xiao, S. Wang, , H. Zhu

The paper develops a high-content Virion Display (VirD) array of human GPCRs to profile their biochemical activities and identifies potential drug targets.

Nature Communications · Apr 30, 2019Peer-reviewedPharmacology & Toxicology

AICAR induces apoptosis and inhibits migration of prostate cancer cells through an AMPK/mTOR-dependent pathway

C.-C. Su, K.-L. Hsieh, S.-C. Wang, H.-C. Yeh, S.-P. Huang, P.-L. Liu, S.-H. Fang, W.-C. Cheng, K.-H. Huang, F.-Y. Chiu, I.-L. Lin, M.-Y. Huang, C.-Y. Li

This study shows AICAR inhibits prostate cancer cell growth, induces apoptosis, reduces migration, and enhances chemosensitivity via the AMPK/mTOR pathway.

bioRxiv · Nov 19, 2018Cancer Biology