Author

F. Brombacher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. F. Savulescu· 1 shared A. Ngomti· 1 shared A. Sher· 1 shared C. R. Mackay· 1 shared D. A. Eccles· 1 shared D. Jankovic· 1 shared E. J. Hyde· 1 shared F. Musaigwa· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. F. Savulescu

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Author profile →

2 papers

Recent·Most cited

Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation.

S. Hadebe, A. F. Savulescu, J. Khumalo, K. Jones, S. Mangali, N. Mthembu, F. Musaigwa, W. Maepa, H. Ndlovu, A. Ngomti, M. Scibiorek, J. Okendo, F. Brombacher

This study shows IgM regulates airway hyperresponsiveness independently of Th2 inflammation in a mouse model of allergic asthma.

eLife · Dec 16, 2025Peer-reviewedImmunology

The skin environment controls local dendritic cell differentiation and function through innate IL-13

J. U. Mayer, O. Lamiable, K. L. Hilligan, J. S. Chandler, S. I. Old, D. A. Eccles, J. Yang, G. R. Webb, R. G. Domingues, L. Munoz-Erazo, K. A. Wakelin, E. J. Hyde, S.-C. Tang, S. C. Chappell, C. R. Mackay, , F. Ronchese

This study shows that IL-13 signaling via STAT6 and KLF4 controls dermal DC2 differentiation and function, shaping a non-inflammatory, pro-allergic skin environment.

bioRxiv · Jan 5, 2021Immunology