Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge
K. L. Hilligan, S. Namasivayam, C. S. Clancy, D. O'Mard, S. D. Oland, S. J. Robertson, P. J. Baker, E. Castro, N. L. Garza, B. A. P. Lafont, R. Johnson, F. Ronchese, K. D. Mayer-Barber, S. M. Best, A. Sher
This study shows that intravenous BCG vaccination protects mice from lethal SARS-CoV-2 infection by altering pulmonary myeloid cell function and reducing immunopathology.
bioRxiv · Aug 30, 2021Immunology