Disruption of HIF1A translational control attenuates the HIF-dependent hypoxic response and solid tumour formation in vivo
J. E. Hunter, O. McHugh, G. B. Ecclestone, F. Child, H. Mearns, G. Robson, M. Dadzie, S. Rocha, N. D. Perkins, N. S. Kenneth
This study shows that disrupting HIF1A translational control reduces hypoxic response and solid tumour formation in mice.
bioRxiv · Nov 2, 2022 · PreprintCancer Biology