Author

F. Esashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. M. Couturier· 2 shared A. El-Sagheer· 1 shared B. G. Davis· 1 shared B. Josephson· 1 shared F. Paoletti· 1 shared J. Allard· 1 shared J. Ellins· 1 shared J.-Y. Bleuyard· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

A. M. Couturier

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Author profile →

3 papers

Recent·Most cited

Intact nucleosomal context enables chromodomain reader MRG15 to distinguish H3K36me3 from -me2

S. Faulkner, A. M. Couturier, B. Josephson, T. Watts, B. G. Davis, F. Esashi

The paper shows MRG15 distinguishes H3K36me3 from H3K36me2 in intact nucleosomes, revealing a methyl-switch mechanism dependent on DNA backbone interactions.

bioRxiv · Apr 30, 2020 · PreprintBiochemistry

KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity

M. Fournier, J.-Y. Bleuyard, A. M. Couturier, J. Ellins, S. Hester, S. J. Smerdon, L. Tora, F. Esashi

This study shows that KAT2A/B acetylates PALB2 to regulate its chromatin association, enhancing DNA repair and genome stability.

bioRxiv · Jan 21, 2020Cell Biology

Molecular flexibility of DNA as a key determinant of RAD51 recruitment

F. Paoletti, A. El-Sagheer, J. Allard, T. Brown, O. Dushek, F. Esashi

This study shows RAD51 binds faster to flexible single-stranded DNA than rigid DNA or double-stranded DNA, suggesting DNA flexibility aids in homologous recombination.

bioRxiv · Jun 25, 2019Biochemistry