nucGEMs probe the biophysical properties of the nucleoplasm
T. Shu, T. Szoradi, G. R. Kidiyoor, Y. Xie, N. L. Herzog, A. Bazley, M. Bonucci, S. Keegan, S. Saxena, F. Ettefa, G. P. Brittingham, J. Lemiere, D. Fenyo, F. Chang, M. Delarue, L. J. Holt
The paper introduces nucGEMs, fluorescent nanoparticles that probe nucleoplasm biophysical properties, revealing differences in motility, exclusion from heterochromatin, and effects of mitotic condensation.
bioRxiv · Nov 18, 2021 · PreprintBiophysics