Probing the stability of the SpCas9-DNA complex after cleavage
P. Aldag, F. Welzel, L. Jakob, A. Schmidbauer, M. Rutkauskas, F. Fettes, D. Grohmann, R. Seidel
This study investigates the stability of SpCas9-DNA complexes after cleavage using single-molecule magnetic tweezers, finding that post-cleavage states are more stable than pre-cleavage states.
bioRxiv · Aug 4, 2021Biophysics