The UIP honeycomb airway cells are the site of mucin biogenesis with deranged cilia
J. A. Herrera, L. A. Dingle, M. A. Montero, V. Rajamiyer, J. Blaikley, F. Granato, S. Pearson, C. Lawless, D. J. Thornton
The paper uses spatial proteomics to compare fibrotic and non-fibrotic airway cells in UIP, finding deregulated pathways and identifying key proteins associated with mucin biogenesis and ciliogenesis.
bioRxiv · Sep 3, 2022Pathology