SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB
C. J. Neufeldt, B. Cerikan, M. Cortese, J. Frankish, J.-Y. Lee, A. Plociennikowska, F. Heigwer, S. Joecks, S. S. Burkart, D. Y. Zander, M. Gendarme, B. El Debs, N. Halama, U. Merle, M. Boutros, , R. Bartenschlager
This study shows SARS-CoV-2 triggers a pro-inflammatory cytokine response via cGAS-STING and NF-κB in epithelial cells, which may contribute to severe disease.
bioRxiv · Jul 21, 2020Microbiology