Author

F. Kloprogge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

A. A. Witney· 1 shared A. Sole· 1 shared F. G. Hernandez· 1 shared G. Mundin· 1 shared J. A. Cordero· 1 shared J. F. Standing· 1 shared J. Ortiz Canseco· 1 shared K. Kipper· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. A. Witney

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2 papers

Recent·Most cited

Named Entity Recognition of Pharmacokinetic parameters in the scientific literature

F. G. Hernandez, Q. Nguyen, V. C. Smith, J. A. Cordero, M. R. Ballester, M. Duran, A. Sole, P. Chotsiri, T. Wattanakul, G. Mundin, W. Lilaonitkul, J. F. Standing, F. Kloprogge

This paper introduces a novel corpus and language models for Named Entity Recognition of pharmacokinetic parameters in scientific literature, achieving high accuracy with BioBERT.

bioRxiv · Feb 12, 2024 · PreprintPharmacology & Toxicology

Understanding emergence of antimycobacterial dose dependent resistance.

F. Kloprogge, J. Ortiz Canseco, L. Phee, Z. Sadouki, K. Kipper, A. A. Witney, N. Stoker, T. D. McHugh

This study investigates how concentration-dependent resistance emerges to isoniazid and rifampicin, showing that genotypic resistance only appears when antibiotic levels fall below MIC, and that isoniazid resistance involves concentration-dependent SNP accumulation.

bioRxiv · Sep 2, 2022 · PreprintPharmacology & Toxicology