Author

Z. Sadouki

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. A. Witney· 1 shared F. Kloprogge· 1 shared J. Ortiz Canseco· 1 shared K. Kipper· 1 shared L. Phee· 1 shared N. Stoker· 1 shared T. D. McHugh· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. A. Witney

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintSep 2, 2022

Understanding emergence of antimycobacterial dose dependent resistance.

F. Kloprogge, J. Ortiz Canseco, L. Phee…·T. D. McHugh

This study investigates how concentration-dependent resistance emerges to isoniazid and rifampicin, showing that genotypic resistance only appears when antibiotic levels fall below MIC, and that isoniazid resistance involves concentration-dependent SNP accumulation.

DOI 10.1101/2022.09.02.506358

experimental assaydrug response / drug discovery

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