T. D. McHugh

The emergence of goblet inflammatory or ITGB6hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis

The study identifies age-related differences in nasal epithelial cell responses to SARS-CoV-2 infection, showing distinct progenitor cell dynamics in children and elderly.

Understanding emergence of antimycobacterial dose dependent resistance.

This study investigates how concentration-dependent resistance emerges to isoniazid and rifampicin, showing that genotypic resistance only appears when antibiotic levels fall below MIC, and that isoniazid resistance involves concentration-dependent SNP accumulation.

Improving diagnosis and monitoring of treatment response in pulmonary tuberculosis using the molecular bacterial load assay (MBLA)

This study evaluates the Molecular Bacterial Load assay (MBLA) for diagnosing and monitoring tuberculosis treatment response, finding it provides reliable, contamination-resistant results faster than traditional methods.