Author

K. Kipper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:fluorescence / live-cell microscopy· 2 Approach:microscopy & imaging analysis· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Amselem· 2 shared E. Marklund· 2 shared J. Elf· 2 shared M. Johansson· 2 shared S. Deindl· 2 shared A. A. Witney· 1 shared A. Emmerich· 1 shared A. Sabantsev· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiophysics

E. Amselem

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Understanding emergence of antimycobacterial dose dependent resistance.

F. Kloprogge, J. Ortiz Canseco, L. Phee, Z. Sadouki, K. Kipper, A. A. Witney, N. Stoker, T. D. McHugh

This study investigates how concentration-dependent resistance emerges to isoniazid and rifampicin, showing that genotypic resistance only appears when antibiotic levels fall below MIC, and that isoniazid resistance involves concentration-dependent SNP accumulation.

bioRxiv · Sep 2, 2022 · PreprintPharmacology & Toxicology

Mechanism of DNA surface exploration and operator bypassing during target search

E. Marklund, B. van Oosten, G. Mao, E. Amselem, K. Kipper, A. Sabantsev, A. Emmerich, D. Globisch, X. Zhen, L. Lehmann, O. Berg, M. Johansson, J. Elf, S. Deindl

This study uses SMCT-FCS to show LacI slides on DNA, bypassing target sequences by hopping out of the DNA groove, revealing a speed-accuracy trade-off in target search.

bioRxiv · Jan 29, 2020Biophysics

Direct observation of rotation-coupled protein diffusion along DNA on the microsecond timescale

E. Marklund, E. Amselem, K. Kipper, X. Zheng, M. Johansson, S. Deindl, J. Elf

This study measures the rotation-coupled diffusion of LacI along DNA, finding it moves ~50 base pairs per revolution, supporting a facilitated diffusion model.

bioRxiv · Aug 27, 2018 · PreprintBiophysics