Uncovering the hidden threat: single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer
M. Le Compte, E. Cardenas De La Hoz, S. Peeters, F. Rodrigues Fortes, C. Hermans, A. Domen, E. Smits, F. Lardon, T. Vandamme, A. Lin, S. Vanlanduit, G. Roeyen, S. Van Laere, H. Prenen, M. Peeters, C. Deben
This study uses single-organoid analysis to identify treatment-resistant and invasive subclones in pancreatic cancer, correlating with patient outcomes and drug response.
bioRxiv · Feb 27, 2023 · PreprintCancer Biology