Mechanically activated bone cells drive vessel formation via an extracellular vesicle mediated mechanism
N. Shen, M. Maggio, I. Woods, K. Eichholz, E. Stavenschi, M. Lowery, F. M. Roche, K. Hokamp, L. O'Driscoll, D. A. Hoey
This study shows mechanically activated bone cells promote vessel formation through extracellular vesicles, which contain miRNAs linked to angiogenesis, offering a potential therapeutic for bone repair.
bioRxiv · Feb 10, 2023 · PreprintBioengineering