Author

D. A. Hoey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 3 Research Focus:cell-cell communication· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. Eichholz· 4 shared I. Woods· 3 shared L. O'Driscoll· 3 shared A. Federici· 2 shared M. Lowery· 2 shared N. Shen· 2 shared B. Tornifoglio· 1 shared C. A. Lally· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersBioengineering

K. Eichholz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Melt electrowritten scaffold architectures to mimic vasculature mechanics and control neo-tissue orientation

A. Federici, B. Tornifoglio, C. A. Lally, O. Garcia, D. Kelly, D. A. Hoey

This study uses melt-electrowriting to create scaffolds mimicking vascular mechanics, showing they support cell alignment and neo-tissue orientation similar to native vessels.

bioRxiv · Apr 17, 2023 · PreprintBioengineering

Mechanically activated bone cells drive vessel formation via an extracellular vesicle mediated mechanism

N. Shen, M. Maggio, I. Woods, K. Eichholz, E. Stavenschi, M. Lowery, F. M. Roche, K. Hokamp, L. O'Driscoll, D. A. Hoey

This study shows mechanically activated bone cells promote vessel formation through extracellular vesicles, which contain miRNAs linked to angiogenesis, offering a potential therapeutic for bone repair.

bioRxiv · Feb 10, 2023 · PreprintBioengineering

Mechanically Activated Extracellular Vesicle Functionalised Melt Electrowritten Materials for Bone Regeneration: A Mechano-Biomimetic Scaffold

K. Eichholz, A. Federici, M. Riffault, I. Woods, O. Mahon, L. O'Driscoll, D. A. Hoey

This study develops a mechano-biomimetic scaffold combining MEW scaffolds with mechanically activated osteocyte-derived EVs to enhance bone regeneration.

bioRxiv · Mar 29, 2021 · PreprintBioengineering

Melt electrowritten scaffolds with bone-inspired fibrous and mineral architectures to enhance BMP2 delivery and human MSC osteogenesis

K. Eichholz, D. A. Hoey

This paper develops scaffolds with bone-mimetic nano-needle HA coatings that enhance BMP2 delivery and MSC osteogenesis for bone tissue regeneration.

bioRxiv · Aug 13, 2019 · PreprintBioengineering

Human bone marrow mesenchymal stem/stromal cell behaviour is coordinated via mechanically activated osteocyte-derived extracellular vesicles

K. Eichholz, I. Woods, G. Johnson, N. Shen, M. Corrigan, M.-N. Labour, K. Wynne, M. Lowery, L. O'Driscoll, D. A. Hoey

This study shows that mechanically activated osteocyte-derived extracellular vesicles enhance human MSC recruitment and osteogenesis, suggesting their potential as a cell-free therapy for bone regeneration.

bioRxiv · Aug 8, 2019 · PreprintPhysiology