Tissue remodeling and cell signaling underpin changes in tumor microenvironment heterogeneity in glioma oncogenesis
M. Dinevska, S. S. Widodo, L. Furst, L. Cuzcano, Y. Fang, S. Mangiola, P. J. Neeson, P. K. Darcy, R. G. Ramsay, F. MacKay, S. S. Stylli, T. Mantamadiotis
The paper shows that glioma progression involves changes in immune cell infiltration, extracellular matrix deposition, and signaling heterogeneity, with implications for therapy.
bioRxiv · Dec 5, 2021Cancer Biology