J. Adams

Does Vibrotactile Stimulation of the Auricular Vagus Nerve Enhance Working Memory? A Behavioral and Physiological Investigation

This study investigates whether vibrotactile taVNS improves working memory performance and arousal, finding significant improvements in performance and reduced arousal decline during high-cognitive-load tasks.

Predicting Serotonin Detection with DNA-Carbon Nanotube Sensors Across Multiple Spectral Wavelengths

The paper uses machine learning to predict serotonin detection by DNA-SWNT sensors across multiple wavelengths, showing DNA sequence's key role and limitations due to dataset size.

The timing of transcription of RpoS-dependent genes varies across multiple stresses in Escherichia coli K-12

This study examines how RpoS-dependent gene transcription timing varies across different stresses in E. coli, showing distinct patterns for stationary phase, high osmolarity, and cold shock.

Topical GZ21T inhibits the growth of actinic keratoses in a UVB induced model of skin carcinogenesis

This study evaluates a topical formulation of GZ17-6.02 (GZ21T) in a murine model of actinic keratoses, showing reduced lesion count and surface area, and prevention of progression to squamous cell carcinoma.

Spatial compartmentalization of signalling imparts source-specific functions on secreted factors

The paper identifies distinct functions of VEGFA from different cell types in skeletal muscle regeneration through time-resolved transcriptomic analysis and functional experiments.

Multifunctional flexible electro-optical arrays for simultaneous spatiotemporal cardiac mapping and modulation

This paper introduces flexible electro-optical devices for simultaneous cardiac mapping and modulation, demonstrating their functionality in real-time spatiotemporal control of cardiac activity.

Conformational flexibility, lipid binding, and regulatory domains in CelTOS

This study identifies key regions and mechanisms of CelTOS pore formation and immunogenicity, with implications for vaccine design against malaria and apicomplexan parasites.

Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

This study identifies endothelial cell Wnt2 and Wnt9b as key regulators of liver zonation and repair, showing their therapeutic potential in acute liver failure using single-cell spatial transcriptomics.

Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens

The paper shows that spatially restricted protease activity in lymph node follicles preserves antigen integrity, leading to stronger GC responses when antigens are targeted to follicular dendritic cells.

Machine learning enables discovery of DNA-carbon nanotube sensors for serotonin

The paper uses machine learning to predict DNA sequences that create strong optical responses to serotonin in DNA-carbon nanotube sensors, discovering five new sensors with improved performance.

The upper respiratory tract microbiome of Australian Aboriginal and Torres Strait Islander children in ear and nose health and disease.

This study examines nasal microbiota in Indigenous Australian children, finding associations between specific bacterial taxa and otitis media status and nose health.

Sensitive high-throughput assays for tumour burden reveal the response of a Drosophila melanogaster model of colorectal cancer to standard chemotherapies

The paper develops high-throughput assays to measure tumour burden in a Drosophila CRC model and shows it responds to standard chemotherapies.

Generation of a New Frizzled 2 Flox Mouse Model to Clarify Its Role in Development

The paper generates a new Fzd2 flox mouse model to investigate tissue-specific roles of Fzd2, resolving contradictions in previous global knockout studies.

Examination of a first-in-class bis-dialkylnorspermidine-terphenyl antibiotic in topical formulation against mono and polymicrobial biofilms

This study evaluates a new antibiotic, CZ-01179, against biofilms using in vitro methods and finds it more effective than current standards in eradicating mature biofilms.

A novel RyR1 inhibitor prevents and rescues sudden death in a mouse model of malignant hyperthermia and heat stroke

This study introduces a novel RyR1 inhibitor that prevents and rescues MH and heat stroke in mouse models, offering improved solubility and clearance compared to dantrolene.

National Wetland Map 5 - and improved spatial extent and representation of inland aquatic and estuarine ecosystems in South Africa

This paper enhances the National Wetland Map version 5 (NWM5) for South Africa, mapping 3.9% of inland aquatic ecosystems and artificial wetlands, with 123% more inland wetlands than the previous version.

Plasmodium male gametocyte development and transmission are critically regulated by general and transmission-specific members of the CAF1/CCR4/NOT complex

This study identifies PyCCR4-1 as a key regulator of male gametocyte development and transmission in Plasmodium, showing its role in mRNA stability and parasite infectivity.