Human thymopoiesis produces polyspecific CD8+ alfa/beta T cells responding to multiple viral antigens
V. Quiniou, P. Barennes, V. Mhanna, P. Stys, H. Vantomme, Z. Zhou, F. Martina, N. Coatnoan, M. Barbie-Sastre, H. P. Pham, B. Clemenceau, H. Vie, M. Shugay, A. Six, B. Brandao, , D. Klatzmann
The paper shows human thymopoiesis produces CD8+ T cells with polyspecific TCRs that recognize multiple viral antigens, supporting broad antiviral immunity.
bioRxiv · Jul 27, 2020Immunology