Interferon-α promotes neo-antigen formation andpreferential HLA-B-restricted antigen presentation in pancreatic β-cells
A. Carre, Z. Zhou, J. Perez-Hernandez, F. Samassa, C. Lekka, A. Manganaro, M. Oshima, H. Liao, R. Parker, A. Nicastri, B. Brandao, M. L. Colli, D. L. Eizirik, M. Göransson, O. Burgos-Morales, , R. Mallone
This study shows that IFN-α increases HLA-B-restricted antigen presentation in pancreatic β-cells, potentially influencing T1D pathogenesis.
bioRxiv · Sep 15, 2023 · PreprintImmunology