A sexually dimorphic hepatic cycle of periportal VLDL generation and subsequent pericentral VLDLR-mediated lipoprotein re-uptake
T. Martini, C. Gobet, A. Salati, J. Blanc, A. Mookhoek, M. Reinehr, G. Knott, J. Sordet-Dessimoz, F. Naef
The paper identifies a sexually dimorphic hepatic cycle of VLDL generation and re-uptake in mice and humans, linking VLDLR expression to cardiovascular risk.
bioRxiv · Oct 7, 2023Physiology