Author

F. Noel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

V. Soumelis· 3 shared C. Hoffmann· 2 shared E. Amblard· 2 shared M. Saichi· 2 shared S. Korniotis· 2 shared A. Surun· 1 shared A. Viguier· 1 shared C. Le Tourneau· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

V. Soumelis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GM-CSF-activated human dendritic cells promote type1 T follicular helper cells (Tfh1) polarization in a CD40-dependent manner

S. Korniotis, M. Saichi, C. Trichot, C. Hoffmann, E. Amblard, A. Viguier, S. Grondin, F. Noel, H. Mattoo, V. Soumelis

This study shows GM-CSF-activated human dendritic cells drive Tfh1 differentiation via CD40-dependent mechanisms, with implications for infections like tuberculosis and COVID-19.

bioRxiv · Apr 28, 2022 · PreprintImmunology

Single cell RNA sequencing of blood antigen-presenting cells in severe Covid-19 reveals multi-process defects in antiviral immunity

M. Saichi, M. Z. Ladjemi, S. Korniotis, C. Rousseau, Z. Ait-Hamou, L. Massenet, E. Amblard, F. Noel, Y. Marie, D. Bouteiller, J. Medvedovic, F. Pene, V. Soumelis

This study uses single-cell RNA sequencing to analyze blood antigen-presenting cells in severe COVID-19 patients, identifying defects in antiviral immunity.

bioRxiv · Jul 20, 2020Immunology

PDL1 AND ICOSL DISCRIMINATE HUMAN SECRETORY AND HELPER DENDRITIC CELLS

C. Hoffmann, F. Noel, M. Grandclaudon, P. Michea, A. Surun, L. Faucheux, P. Sirven, J. Rochefort, O. Lantz, J. Klijanienko, C. Lecerf, M. Kamal, C. Le Tourneau, M. Guillot-Delost, V. Soumelis

The paper identifies two functional states of human activated dendritic cells, secretory DC and helper DC, distinguished by PDL1 and ICOSL expression and their distinct cytokine profiles and T cell stimulation capacities.

bioRxiv · Aug 1, 2019 · PreprintImmunology