Author

M. Kamal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Physiology· 2 Biochemistry· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. Surun· 2 shared B. F. Miller· 2 shared C. Hoffmann· 2 shared C. Le Tourneau· 2 shared C. Lecerf· 2 shared J. Klijanienko· 2 shared M. Guillot-Delost· 2 shared M. Stout· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

A. Surun

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice

S. Ali Mondal, S. Mann, C. van der Linden, R. Sathiaseelan, M. Kamal, S. Das, M. Bubak, S. Logan, B. F. Miller, M. Stout

This study shows that 17α-estradiol's metabolic benefits in male mice are partially mediated by ERβ in liver, specifically affecting SCD1 and TGF-β1 production.

bioRxiv · Mar 25, 2023 · PreprintPhysiology

17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

S. Ali Mondal, R. Sathiaseelan, S. Mann, M. Kamal, W. Luo, T. Saccon, J. Isola, R. Peeler, T. Li, W. M. Freeman, B. Miller, M. Stout

This study shows that 17-E2 reduces liver fibrosis in male mice by decreasing collagen synthesis and increasing collagen degradation.

bioRxiv · Jun 16, 2022Physiology

Senolytic Treatment Reduces Cell Senescence and Necroptosis in Sod1 Knockout Mice that is Associated with Reduced Inflammation and Hepatocellular Carcinoma

N. Thadathil, R. Selvarani, S. J. Mohammed, E. H. Nicklas, A. L. Tran, M. Kamal, W. Luo, J. L. Brown, M. M. Lawrence, A. K. Borowik, B. F. Miller, H. Van Remmen, A. Richardson, S. S. Deepa

bioRxiv · May 15, 2022Biochemistry

A Rapid in vivo Pipeline to Identify Small Molecule Inhibitors of Amyloid Aggregation

M. Kamal, J. Knox, R. I. Horne, O. S. Tiwari, A. Burns, D. Han, D. L. Bar-Yosef, E. Gazit, K. C. Nguyen, D. H. Hall, M. Vendruscolo, P. J. Roy

This paper presents an in vivo pipeline to identify small molecule inhibitors of amyloid aggregation by screening compounds that suppress crystal formation in C. elegans.

bioRxiv · Apr 11, 2022 · PreprintPharmacology & Toxicology

A small molecule screen identified N-Acetyl-L-cysteine for promoting ex vivo growth of single circulating tumor cells

T. Teng, M. Kamal, O. Iriondo, Y. Amzaleg, C. Luo, A. Thomas, G. Lee, J. D. Nguyen, A. Smith, R. Sposto, M. Yu

The paper identifies N-acetylcysteine (NAC) as a compound that promotes ex vivo growth of single circulating tumor cells by reducing oxidative stress.

bioRxiv · Aug 19, 2020 · PreprintCancer Biology

Imaging-Genomics Study Of Head-Neck Squamous Cell Carcinoma: Associations Between Radiomic Phenotypes And Genomic Mechanisms Via Integration Of TCGA And TCIA

Y. Zhu, A. S. Mohamed, S. Y. Lai, S. Yang, A. Kanwar, L. Wei, M. Kamal, S. Sengupta, H. Elhalawani, H. Skinner, D. S. Mackin, J. Shiao, J. Messer, A. Wong, Y. Ding, , C. D. Fuller

This study integrates radiomic and genomic data from HNSCC patients to find associations between imaging features and genomic biomarkers, achieving moderate predictive accuracy for HPV and TP53 mutation status.

JCO Clinical Cancer Informatics · Dec 1, 2019Peer-reviewedCancer Biology

MMP2 As An Independent Prognostic Stratifier In Oral Cavity Cancers

C. Hoffmann, S. Vacher, P. Sirven, C. Lecerf, L. Massenet, A. Moreira, A. Surun, A. Schnitzler, J. Klijanienko, O. Mariani, E. Jeannot, N. Badois, M. Lesnik, O. Choussy, C. Le Tourneau, , V. Soumelis

The paper identifies MMP2 as an independent prognostic biomarker for oral cavity cancers, associated with poor disease-specific survival.

bioRxiv · Aug 2, 2019Cancer Biology

PDL1 AND ICOSL DISCRIMINATE HUMAN SECRETORY AND HELPER DENDRITIC CELLS

C. Hoffmann, F. Noel, M. Grandclaudon, P. Michea, A. Surun, L. Faucheux, P. Sirven, J. Rochefort, O. Lantz, J. Klijanienko, C. Lecerf, M. Kamal, C. Le Tourneau, M. Guillot-Delost, V. Soumelis

The paper identifies two functional states of human activated dendritic cells, secretory DC and helper DC, distinguished by PDL1 and ICOSL expression and their distinct cytokine profiles and T cell stimulation capacities.

bioRxiv · Aug 1, 2019 · PreprintImmunology