Author

O. Lantz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1

Frequent Co-Authors

S. Amigorena· 3 shared C. Goudot· 2 shared J. Fuentealba· 2 shared A. Darbois· 1 shared A. Seguin-Givelet· 1 shared A. Surun· 1 shared A. Sutra Del Galy· 1 shared A. Walczak· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersImmunology

S. Amigorena

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Author profile →

4 papers

Recent·Most cited

Epigenetic control of CD8+ T cell tissue homing and tissue resident memory T cell precursors by the histone methyltransferase SUV39H1

G. Suarez, S. Heurtebise-Chretien, P.-E. Bonte, H. Beuchet, J. Fuentealba, C. Goudot, O. Lantz, S. Amigorena

This study shows that SUV39H1 depletion in CD8+ T cells enhances tissue homing and TRM differentiation, improving therapeutic outcomes in infection and cancer.

bioRxiv · May 13, 2024 · PreprintImmunology

In vivo genome-wide CRISPR screens identify SOCS1 as a major intrinsic checkpoint of CD4+ Th1 cell response

A. Sutra Del Galy, S. Menegatti, J. Fuentealba, F. Lucibello, J. Helft, A. Darbois, M. Saitakis, J. Tosello, D. Rookhuizen, L. Perrin, M. Deloger, P. Gestraud, G. Socie, S. Amigorena, O. Lantz, L. Menger

The paper identifies SOCS1 as a key intrinsic checkpoint limiting CD4+ Th1 cell response through in vivo CRISPR screens and shows targeting SOCS1 enhances antitumor T-cell therapy.

bioRxiv · Apr 12, 2021Immunology

Contribution of resident and circulating precursors to tumor-infiltrating CD8+ T cell populations in non-small cell lung cancer patients

C. Metoikidou, P. Gueguen, T. Dupic, M. Lawand, C. Goudot, S. Baulande, S. Lameiras, O. Lantz, N. Girard, A. Seguin-Givelet, M. Lefevre, T. Mora, A. Walczak, J. J. Waterfall, S. Amigorena

The paper identifies two CD8+ TIL subpopulations in NSCLC, one circulating and one resident, which transition into terminally differentiated cells through a unique state.

bioRxiv · Aug 14, 2020Immunology

PDL1 AND ICOSL DISCRIMINATE HUMAN SECRETORY AND HELPER DENDRITIC CELLS

C. Hoffmann, F. Noel, M. Grandclaudon, P. Michea, A. Surun, L. Faucheux, P. Sirven, J. Rochefort, O. Lantz, J. Klijanienko, C. Lecerf, M. Kamal, C. Le Tourneau, M. Guillot-Delost, V. Soumelis

The paper identifies two functional states of human activated dendritic cells, secretory DC and helper DC, distinguished by PDL1 and ICOSL expression and their distinct cytokine profiles and T cell stimulation capacities.

bioRxiv · Aug 1, 2019 · PreprintImmunology