Author

F. Offner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Van Parys· 1 shared B. Vandekerckhove· 1 shared D. Clarisse· 1 shared D. Fijalkowska· 1 shared E. Depla· 1 shared E. Pascal· 1 shared E. Staessens· 1 shared G. Acke· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Van Parys

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Crosstalk between the glucocorticoid and mineralocorticoid receptor boosts glucocorticoid-induced killing of multiple myeloma cells

D. Clarisse, S. Prekovic, P. Vlummens, E. Staessens, K. Van Wesemael, J. Thommis, D. Fijalkowska, G. Acke, W. Zwart, I. M. Beck, F. Offner, K. De Bosscher

This study shows that combining dexamethasone with spironolactone enhances myeloma cell killing through GR-MR crosstalk, with potential for dose reduction.

bioRxiv · May 10, 2023Cancer Biology

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen induced exhaustion

S. De Munter, J. Buhl, L. De Cock, A. Van Parys, W. Daneels, E. Pascal, L. Deseins, J. Ingels, G. Goetgeluk, L. Billiet, M. Pille, N. Vandamme, J. Van Dorpe, F. Offner, E. Depla, , B. Vandekerckhove

The paper shows that knocking out CD70 in CD70-specific nanoCAR T cells improves their functionality in vivo by preventing antigen-induced exhaustion.

bioRxiv · Jan 22, 2023Immunology