Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
H. Dohnalova, M. Seifert, E. Matouskova…·F. Lankas
This study investigates how temperature affects the twist of double-stranded RNA using magnetic tweezers and molecular dynamics simulations, finding RNA unwinds more than DNA with increasing temperature.
S. C. Bera, P. P. B. America, S. Maatsola…·D. Dulin
The paper quantifies the kinetics of bacterial RNA polymerase open-complex formation, stabilization, and disruption on a consensus promoter using single-molecule magnetic tweezers.
S. C. Bera, M. Seifert, R. Kirchdoerfer…·D. Dulin
This study describes the mechanochemical behavior of the SARS-CoV-2 polymerase using magnetic tweezers, revealing three catalytic conformations and a thermal ratchet mechanism for nucleotide incorporation.
M. Seifert, S. C. Bera, P. van Nies…·D. Dulin
This study investigates how nucleotide analogs like Remdesivir affect SARS-CoV-2 polymerase activity using single-molecule techniques, revealing backtracking rather than termination and evasion of ddhCTP.
M. Seifert, P. van Nies, F. S. Papini…·D. Dulin
This study uses temperature-controlled magnetic tweezers to compare replication kinetics of RdRps from three RNA viruses, finding temperature-dependent activation differences.