Author

F. Safi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

G. Karlsson· 4 shared P. Dhapola· 4 shared M. N. E. Sommarin· 3 shared D. Bryder· 2 shared E. Erlandsson· 2 shared L. Geironson Ulfsson· 2 shared R. Krishna Thakur· 2 shared R. Warfvinge· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersCell Biology

G. Karlsson

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Author profile →

4 papers

Recent·Most cited

CD9 marks myeloid/MegE-biased human hematopoiesis

F. Safi, P. Dhapola, M. N. E. Sommarin, G. Karlsson

The paper investigates CD9 expression in human hematopoietic stem and progenitor cells (HSPCs) over time, finding that CD9 marks progenitors with high proliferation capacity and is upregulated during myeloid/MegE-biased hematopoiesis.

bioRxiv · Sep 6, 2023 · PreprintCell Biology

Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

R. Warfvinge, L. Geironson Ulfsson, P. Dhapola, F. Safi, M. N. E. Sommarin, S. Soneji, H. Hjorth-Hansen, S. Mustjoki, J. Richter, R. Krishna Thakur, G. Karlsson

This paper uses single-cell multi-omics to analyze CML patient data, showing that cellular heterogeneity correlates with therapy response and identifies markers for LSCs and HSCs.

bioRxiv · Aug 16, 2023 · PreprintCancer Biology

Single-Cell Multiomics Reveals Distinct Cell States at the Top of the Human Hematopoietic Hierarchy

M. N. E. Sommarin, P. Dhapola, F. Safi, R. Warfvinge, L. Geironson Ulfsson, E. Erlandsson, A. Konturek-Ciesla, R. Krishna Thakur, C. Böiers, D. Bryder, G. Karlsson

This study uses single-cell multiomics to reveal distinct cell states in human hematopoietic stem and progenitor cells, showing a bifurcation into lineage-specific trajectories and changes with age.

bioRxiv · Apr 1, 2021 · PreprintCell Biology

Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction

F. Safi, P. Dhapola, S. Warsi, E. Erlandsson, E. Sitnicka, D. Bryder, C. Boiers, R. K. Thakur, G. Karlsson

The paper identifies a transitional cell population in hematopoietic stem/progenitor cells that concurrently exhibit stem-like and lineage-affiliated chromatin signatures, indicating early lineage priming.

bioRxiv · Apr 29, 2020Cell Biology