Author

D. Bryder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:scATAC-seq· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

A. Konturek-Ciesla· 2 shared E. Erlandsson· 2 shared F. Safi· 2 shared G. Karlsson· 2 shared P. Dhapola· 2 shared A. Baudet· 1 shared A. Dahl· 1 shared A. Gerbaulet· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

A. Konturek-Ciesla

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Author profile →

5 papers

Recent·Most cited

Ex vivo Expansion Potential of Murine Hematopoietic Stem Cells: A Rare Property Only Partially Predicted by Phenotype

Q. Zhang, R. Olofzon, A. Konturek-Ciesla, O. Yuan, D. Bryder

This study examines ex vivo expansion of murine HSCs, finding that only a rare subset exhibits functional self-renewal, which is not fully predicted by phenotype.

bioRxiv · Jun 20, 2022 · PreprintCell Biology

Single-Cell Multiomics Reveals Distinct Cell States at the Top of the Human Hematopoietic Hierarchy

M. N. E. Sommarin, P. Dhapola, F. Safi, R. Warfvinge, L. Geironson Ulfsson, E. Erlandsson, A. Konturek-Ciesla, R. Krishna Thakur, C. Böiers, D. Bryder, G. Karlsson

This study uses single-cell multiomics to reveal distinct cell states in human hematopoietic stem and progenitor cells, showing a bifurcation into lineage-specific trajectories and changes with age.

bioRxiv · Apr 1, 2021 · PreprintCell Biology

Hepatic Leukemia Factor supports the propagation of leukemia and hematopoietic stem cell function during stress-induced regeneration.

A. Baudet, K. Komorowska, S. Hultmark, M. Chapellier, K. Miharada, J. Larsson, D. Bryder, M. Jaras, G. Juliusson, M. Magnusson

This study shows HLF is essential for stress-induced hematopoietic regeneration and leukemia propagation in aged HSCs but not for normal aging hematopoiesis.

bioRxiv · Mar 5, 2021 · PreprintCancer Biology

Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction

F. Safi, P. Dhapola, S. Warsi, E. Erlandsson, E. Sitnicka, D. Bryder, C. Boiers, R. K. Thakur, G. Karlsson

The paper identifies a transitional cell population in hematopoietic stem/progenitor cells that concurrently exhibit stem-like and lineage-affiliated chromatin signatures, indicating early lineage priming.

bioRxiv · Apr 29, 2020Cell Biology

Proliferative behavior of hematopoietic stem cells revisited: No evidence for mitotic memory

M. N. F. Morcos, T. Zerjatke, I. Glauche, C. M. Munz, Y. Ge, A. Petzold, S. Reinhardt, A. Dahl, N. Anstee, R. Bogeska, M. Milsom, P. Saewen, H. Wan, D. Bryder, A. Roers, A. Gerbaulet

The paper revisits the proliferative behavior of hematopoietic stem cells (HSCs) and finds no evidence for mitotic memory or permanent quiescence after few divisions.

bioRxiv · Aug 28, 2019Cell Biology