Rotavirus Induces Intercellular Calcium Waves Through ADP Signaling
A. C. Chang-Graham, J. L. Perry, M. A. Engevik, H. A. Danhof, F. Scribano, K. A. Engevik, J. Nelson, J. S. Kellen, A. C. Strtak, N. S. Palla, M. K. Estes, J. Versalovic, R. A. Britton, J. M. Hyser
This study shows rotavirus induces intercellular calcium waves via ADP signaling, which amplifies diarrheal symptoms and can be blocked by P2Y1 antagonists or knockout.
bioRxiv · Dec 31, 2019Microbiology