BiophysicsbioRxivPreprint
Universal amyloidogenicity of patient-derivedimmunoglobulin light chains
R. Sternke-Hoffmann, T. Pauly, R. K. Norrild…·A. K. Buell
This study shows that all tested patient-derived immunoglobulin light chains have comparable amyloidogenic potential, with proteolytic cleavage being a key determinant of in vivo aggregation.
DOI 10.1101/2021.05.12.443858