The CARD-CC/Bcl10/paracaspase signaling complex is functionally conserved since the last common ancestor of planulozoa.
J. Staal, Y. Driege, A. Borghi, P. Hulpiau, L. Lievens, I. Gul, S. Sundararaman, A. Goncalves, I. Dhondt, B. Braeckman, U. Technau, Y. Saeys, F. Van Roy, R. Beyaert
This study identifies the ancient conservation of the CARD-CC/Bcl10/paracaspase signaling complex across planulozoa, including invertebrates and vertebrates.
bioRxiv · Aug 16, 2016Evolutionary Biology