F. Vincent

Structural basis for CCR6 modulation by allosteric antagonists

This paper presents two inactive CCR6 structures bound to allosteric antagonists, revealing structural insights into CCR6 inhibition and its implications for drug discovery.

Homing in on the rare virosphere reveals the native host of giant viruses

The paper uses single-cell metatranscriptomics to identify the native hosts of giant viruses in marine plankton communities, revealing a rare host-virus relationship and viral control of host population dynamics.

Viral infection switches the balance between bacterial and eukaryotic recyclers of organic matter during algal blooms

The paper investigates how viral infection affects carbon cycling in algal blooms by altering the balance between bacterial and eukaryotic organic matter recyclers.

Sortilin exhibits tumor suppressor-like activity by limiting EGFR transducing function

This study shows sortilin limits EGFR's transducing function by interacting with gene regulatory elements, suggesting it may predict anti-EGFR therapy efficacy in lung adenocarcinoma.

Viral infection of algal blooms leaves a halogenated footprint on the dissolved organic matter in the ocean

The paper investigates the metabolic changes in dissolved organic matter (DOM) caused by viral infection of algal blooms, identifying halogenated metabolites as biomarkers of viral-induced bloom demise.