PP2A forestalls mitophagy by dephosphorylating Parkin and ubiquitin
S.-X. Ye, X.-Y. Liu, Z.-F. Nie, L.-S. Meng, X. Dong, F.-F. Li, Z. Gong, W. Yang, W.-P. Zhang, C. Tang
This study identifies PP2A as a phosphatase that dephosphorylates Parkin and ubiquitin, thereby inhibiting mitophagy.
bioRxiv · Mar 12, 2022 · PreprintBiochemistry